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Bromethalin toxicity in dogs and cats | VETgirl Veterinary CE Podcasts

Bromethalin is a mouse and rat poison that may sound like brodifacoum or bromadiolone, but it has nothing to do with Vitamin K1 or coagulopathy. Bromethalin results in cerebral edema and has a narrow margin of safety. Check out this VetGirl veterinary podcast to learn more about this rodenticide that is becoming more prevalent due to new EPA mandates!

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  1. We recently had a dog come in to my hosptial after ingestion of a very large toxic dose of bromethalin. Thankfully he never developed any clinical signs but apparently position control gave a very grave prognosis if symptoms were to develop and therefore euthanasia was advised over treatment should the dog develop any signs of cerebral edema. Is this the best course of action? What is the prognosis once symptoms have started? Also poison control informed us that there is an acute onset but also can get a delayed reaction up to weeks after ingestion. In the chronic form dogs could develop paresis or paralysis up to weeks after administration while they were more likely to get tremors and seizures in the acute form. I have not heard of the chronic/delayed reaction before. Can you elaborate?

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