Podcasts

Intravenous lipid emulsion (ILE) with ivermectin toxicity in dogs : Getting the skinny on using fat! | VETgirl Veterinary CE Podcasts

In today’s VETgirl online veterinary continuing education podcast, we review the use of intravenous lipid emulsion (ILE), otherwise known as intravenous fat emulsion (IFE), in veterinary medicine. ILE has been documented in both human and veterinary medicine as a possible antidote for fat-soluble drug toxicities such as macrocylic lactones (e.g., ivermectin, moxidectin), local anesthetics, baclofen, cholecalciferol, etc.).  In this VETgirl podcast, we discuss how ILE works, what toxins it is effective for, and how to use this exciting antidote option.

References:
1. Fernandez AL, Lee JA, Rahilly L, et al. The use of intravenous lipid emulsion as an antidote in veterinary toxicology. J Vet Emerg Crit Care 2011;21(4):309-20.

2. Crandell DE, Weinberg GL. Moxidectin toxicosis in a puppy successfully treated with intravenous lipids. J Vet Emerg Crit Care 19(2):181-186, 2009.

3. Jamaty C et al: Lipid emulsions in the treatment of acute poisoning: a systematic review of human and animal studies, Clin Toxicol 48:1–27, 2010.

4. Weinberg G et al: Lipid emulsion infusion rescues dogs from bupivacaine-induced cardiac toxicity, Reg Anesth Pain Med 28:198-202, 2003.

5. Herring JM, McMichael MA, Corsi, et al. Intravenous lipid emulsion therapy in three cases of canine naproxen overdose. J Vet Emerg Crit Care 2015;25(5):672-678.

Thanks to ASPCA Animal Poison Control Center for sponsoring this VETgirl podcast!

ASPCA logo Nov 2015

Questions? You can always contact us via our Contact Us page.

Only VETgirl members can leave comments. Sign In or Join VETgirl now!