In this VETgirl online veterinary CE blog, we are observing a cat with ventroflexion of the neck. Typically, causes of ventroflexion in a cat include differential diagnoses such as systemic or metabolic disease. Examples include hypokalemia, thiamine deficiency, hyperthyroidism, and chronic renal disease. Other less common causes include other electrolyte abnormalities (e.g., hypocalcemia, hypernatremia, etc.), neuromuscular disease (e.g., polymyositis, myasthenia gravis), central nervous system disease, polyneuropathy, hereditary causes (e.g., seen in breeds such as the Bermese cat), and toxicosis (e.g., ammonium chloride, organophosphates, etc.).