[iframe style=”border:none” src=”https://html5-player.libsyn.com/embed/episode/id/2655325/height/45/width/450/thumbnail/no/theme/standard” height=”45″ width=”450″ scrolling=”no” allowfullscreen webkitallowfullscreen mozallowfullscreen oallowfullscreen msallowfullscreen]

In today’s VetGirl blog, we interview Dr. Bill Bush, DACVIM (Neurology) of Bush Veterinary Neurology Services on his favorite anti-convulsant to use in veterinary medicine. So, why keppra, a newer anti-epileptic drug, instead of phenobarbital or potassium bromide? Is it effective? How expensive is it? Should it be my first choice drug for my epileptic patients? Dr. Bush discusses some of the pros: the generic version of the extended release product (making it cost-effective) and its minimal side effects (e.g., aside from sedation, ataxia, etc.).  Check out this VetGirl blog to learn if you should be using it!

  1. What’s the best way to switch to Keppra as a monotherapy from phenobarbital or potassium bromide? Any anecdotal advice?

  2. I had a question about what he means when he says to “work up to 50 mg/kg”. Does that mean he uses that as his end dose for all seizure patients or only work up if seizures are not controlled at 30 mg/kg BID? Thank you!! 🙂

    • Work up to it means gradually increase the dose to control the seizures but ideally use the lowest effective dose to control (< 1 seizure q. 3 months, as a goal).

  3. My take away- start using Keppra in an emergency setting on that seizuring or cluster dog either IV @60mg/kg – what is the SQ dose? Same?

Leave a Reply

Your email address will not be published. Required fields are marked *